Mission-driven work
Every experiment brings us closer to therapies that could prevent Alzheimer's, stop Parkinson's, or extend healthspan for millions.
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Mission-driven science in protein engineering, delivery systems, and translational therapeutics.
Mission-driven science in protein engineering, delivery systems, and translational therapeutics.
Why Tiragena?Why Tiragena?
We combine deep scientific expertise with the agility of an early-stage biotech—building therapies that could change how we treat neurodegeneration.
We combine deep scientific expertise with the agility of an early-stage biotech—building therapies that could change how we treat neurodegeneration.
Cutting-edge science
Work with technology 5–10 years ahead of the field:
- Genetic Code Expansion platforms
- Non-canonical amino acid chemistry
- VLP/LNP delivery engineering
- Protein aggregation mechanisms
Ground floor opportunity
Shape culture, wear multiple hats, and grow rapidly with direct impact on company success.
- Equity participation
- Direct founder interaction
- Multi-disciplinary exposure
World-class mentorship
Collaborative, non-hierarchical environment with encouragement to publish and present.
- 100+ publications from founders
- Support for continued education
- Conference participation
Work–life balance
Winnipeg offers affordable living and short commutes with flexible arrangements.
- Competitive benefits
- Flexible working
- Supportive atmosphere
Current openings
All roles are based in Winnipeg, MB unless noted. Send CV and cover letter to info@tiragena.com with the role title in the subject line.
Research Scientist — Protein Engineering
Lead development of ncAA-modified proteins for Phase I product line and therapeutic applications.
Responsibilities
- Design and express proteins with site-specific ncAA incorporation
- Optimize orthogonal translation systems
- Characterize proteins by mass spec and functional assays
- Support product manufacturing and publications
Qualifications
- PhD in biochemistry, molecular biology, or related field
- Recombinant protein expression (E. coli, mammalian)
- Protein purification and characterization
- GCE or ncAA experience preferred
Competitive salary + equity + benefits
ApplySenior Scientist — Delivery Systems
Develop VLP and LNP delivery platforms for in vivo protein editing therapies.
Responsibilities
- Engineer VLP capsids for tissue targeting
- Optimize LNP formulations for CNS delivery
- Characterize particles and conduct in vivo studies
- Collaborate on regulatory strategy
Qualifications
- PhD + 3–5 years in gene therapy or mRNA therapeutics
- Viral vector or LNP production experience
- GMP manufacturing knowledge
- In vivo study experience
Competitive salary + equity + benefits
ApplyResearch Associate — Protein Characterization
Perform analytical characterization of engineered proteins and support QC.
Responsibilities
- Mass spectrometry (LC-MS, MALDI-TOF)
- Protein purification (FPLC)
- Functional assays and documentation
- Support GMP documentation
Qualifications
- BSc or MSc in biochemistry or chemistry
- Analytical instrumentation experience
- GLP/GMP familiarity preferred
Competitive salary + benefits
ApplyScientist — Medicinal Chemistry
Synthesize and characterize novel non-canonical amino acids for therapeutic applications.
Responsibilities
- Design and synthesize ncAAs
- Optimize synthetic routes for scale-up
- Characterize by NMR and mass spec
- Support IP development
Qualifications
- PhD in organic or medicinal chemistry
- Strong synthetic chemistry skills
- Amino acid chemistry experience preferred
Competitive salary + equity + benefits
ApplyComputational Biologist
Use computational approaches to predict optimal ncAA incorporation sites and protein modifications.
Responsibilities
- Analyze protein structures for modification sites
- Model ncAA-modified proteins
- Develop bioinformatics pipelines
- Analyze NGS data from expression libraries
Qualifications
- PhD in bioinformatics or computational biology
- Protein structure prediction experience
- Python/R proficiency
- Molecular dynamics familiarity
Competitive salary + equity + benefits
ApplyBusiness Development Associate
Support commercialization of Phase I products and identify partnership opportunities.
Responsibilities
- Identify customers and partners
- Prepare partnership proposals
- Market research and competitive analysis
- Attend conferences (20–30% travel)
Qualifications
- Life sciences degree + MBA or BD experience
- Biotech/pharma industry understanding
- Excellent communication skills
Competitive salary + equity + commission
ApplyInternships & co-op positions
Students welcome in protein engineering, synthetic biology, medicinal chemistry, biomanufacturing, and computational biology.
Responsibilities
- Duration: 4–12 months
- Hands-on lab or computational projects
- Mentorship from senior scientists
Qualifications
- Enrolled in relevant degree program
- Strong academic record
- Team-oriented mindset
Competitive stipend
ApplyReady to apply?
Email your CV and cover letter with the role title in the subject line.